Now & Future December Series Session #1: Microelectronics and Microsystems for Real-Time Bio-Sensing Devices

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The sessions in the Now & Future Series were open to the audience. A complete journey around Bioelectronics for implantable and Wearable Devices has been delivered.

By Dr. Sara Ghoreishizadeh. Continuous, real-time, and non-invasive measurement of vital parameters (specifically, chemical biomarkers) in the human body could address unmet clinical needs in healthcare monitoring, personalized therapy, closed-loop drug dosage, and managing pain and chronic health conditions. Various molecular components, including enzymes, hormones, and antibodies commonly found via invasive blood testing, are accurately reflected in other body fluids such as interstitial fluid, saliva, and sweat. However, the potential of non-blood biofluids in reflecting an individual's health condition in real-time has not been harvested because of the absence of suitable analysis technology.

This seminar gives an overview of our recent research on subcutaneous and wearable biosensors, emphasizing microelectronics' role in allowing miniaturization, full integration, and autonomy of such devices. We also present a brief account of our ongoing search for a biofluid-based biomarker of nociception and wearable devices that may allow their measurement.