The precise detection and segmentation of cells in microscopic image sequences is an essential task in biomedical research, such as drug discovery and studying the development of tissues, organs, or entire organisms. However, the detection and segmentation of cells in phase contrast images with a halo and shade-off effects is still challenging. Lately, Mask Regional Convolutional Neural Network (Mask R-CNN) has been introduced for object detection and instance segmentation of natural images. This study investigates the efficacy of the Mask R-CNN to instantly detect and segment label-free

In this paper, we propose an effective saliency detection method based on dense and sparse representation in-terms of an optimized background template. Firstly, the input image is divided into compact and uniform super-pixels. Then, the optimized background template is produced by introducing boundary conductivity measurement to improve the dense and sparse representation of the image's super-pixels in terms of the optimized background, where the reconstruction error represents a saliency measure. Based on the optimized template, two saliency maps are generated by dense and sparse

This Electronic Health (E-Health) is a broad expression that enables the communication between healthcare professionals in handling patient information through the cloud. Exchanging medical data over the public cloud requires securing transferring for the data that's direct many researchers in proposing different secure schemes to enable users to handle data safely without hacking or alternating. In this study, one of the most common encryption algorithms called Triple Data Encryption Standard (Triple-DES) has been implemented with the aid of the hash function and DNA cryptography base to

Transforming growth factor beta (TGF-β) acts as a tumor-suppressing cytokine in healthy tissues and non-malignant tumors. Yet, in malignancy, TGF-β can exert the opposite effects that can promote proliferation of cancer cells. C-Kit plays a prominent role in stem cell activation and liver regeneration after injury. However, little is known about the cross-talk between TGF-β and C-Kit and its role in the progression of hepatocellular carcinoma (HCC). Here, we studied the effect of increasing doses of TGF-β1 on CD44+CD90+ liver stem cells (LSCs) and C-Kit gene expression in malignant and

Dynamic programming is a mathematical optimization first invented in 1950s and lived till our times to make optimizations and reduce complexity in several different fields like bioinformatics, Electric vehicles, energy consumption, medical field and much more as a proof of being a powerful technique. In this paper, the various fields and aspects in which Dynamic programming has a significant contribution are surveyed. © 2020 IEEE.

Although the majority of existing License Plate (LP) recognition techniques have significant improvements in accuracy, they are still limited to ideal situations in which training data is correctly annotated with restricted scenarios. Moreover, images or videos are frequently used in monitoring systems that have Low Resolution (LR) quality. In this work, the problem of LP detection in digital images is addressed in the images of a naturalistic environment. Single-stage character segmentation and recognition are combined with adversarial Super-Resolution (SR) approaches to improve the quality

OBJECTIVES Minimally invasive aortic valve replacement has proven its value over the last decade by its significant advancement and reduction in mortality, morbidity and admission time. However, minimally invasive aortic valve replacement is associated with some on-site difficulties such as limited aortic annulus exposure. Currently, computed tomography scans are used to evaluate the anatomical relationship among the intercostal spaces, ascending aorta and aortic valve prior to surgery. We hypothesized that quantitative measurements of access distance and access angle are associated with

Feature selection is critical in analyzing microarray data, which has many features (genes) or dimensions. However, with only a few samples the large search space and time consumed during their selection make selecting relevant and informative genes that improve classification performance a complex task. This paper proposed a hybrid model for gene selection known as (SVM-mRMRe), the proposed model provides a framework for combining filter-based, ensemble, and embedded methods to select the most relevant and informative genes from high-dimensional microarray data by fusing embedded SVM

Cancer can be considered as one of the leading causes of death widely. One of the most effective tools to be able to handle cancer diagnosis, prognosis, and treatment is by using expression profiling technique which is based on microarray gene. For each data point (sample), gene data expression usually receives tens of thousands of genes. As a result, this data is large-scale, high-dimensional, and highly redundant. The classification of gene expression profiles is considered to be a (NP)-Hard problem. Feature (gene) selection is one of the most effective methods to handle this problem. A

Skin cancer is one of the leading causes of death globally. Early diagnosis of skin lesion significantly increases the prevalence of recovery. Automatic classification of the skin lesion is a challenging task to provide clinicians with the ability to differentiate between different kind of lesion categories and recommend the suitable treatment. Recently, Deep Convolutional Neural Networks have achieved tremendous success in many machine learning applications and have shown an outstanding performance in various computer-assisted diagnosis applications. Our goal is to develop an automated