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Analysis of the current situation of pharmacogenomics in terms of educational and healthcare needs in Egypt and Lebanon
Pharmacogenomics (PGx) is a practice that investigates the link between genetic differences and drug response in patients. This can improve treatment effectiveness and reduce harmful side effects. However, has yet to be adequately realized in developing nations. Three surveys were conducted between November 2022 to March 2023 in Egypt and Lebanon. The first survey assessed availability of PGx
ArabicQuest: Enhancing Arabic Visual Question Answering with LLM Fine-Tuning
In an attempt to bridge the semantic gap between language understanding and visuals, Visual Question Answering (VQA) offers a challenging intersection of computer vision and natural language processing. Large Language Models (LLMs) have shown remarkable ability in natural language understanding; however, their use in VQA, particularly for Arabic, is still largely unexplored. This study aims to
Early detection of hypo/hyperglycemia using a microneedle electrode array-based biosensor for glucose ultrasensitive monitoring in interstitial fluid
Diabetes is a common chronic metabolic disease with a wide range of clinical symptoms and consequences and one of the main causes of death. For the management of diabetes, painless and continuous interstitial fluid (ISF) glucose monitoring is ideal. Here, we demonstrate continuous diabetes monitoring using an integrated microneedle (MN) biosensor with an emergency alert system. MNs are a novel
Predicting energy consumption of mosque buildings during the operation stage using deep learning approach
The energy consumption resulting from the construction sector is increasing rapidly. Different building types have different energy consumption schemes, especially during their operational stage. Among these types of buildings, mosques are considered one of the intermittent building types that suffer from huge energy wastage. That's why there is a need to monitor their operational performance
Estimate of Power Output from Hydraulic Jumps Generated Downstream from Barrages
Hydropower is an affordable, sustainable way to generate electricity. Research on hydraulic jumps focuses only on determining head loss across the jump, but there are no studies on generating power from the jump. This research aims to utilize energy dissipated from hydraulic jumps for power-generating purposes and further use this power in real-life applications. This research simulates ideal
Mitoepigenetics pathways and natural compounds: a dual approach to combatting hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a leading liver cancer that significantly impacts global life expectancy and remains challenging to treat due to often late diagnoses. Despite advances in treatment, the prognosis is still poor, especially in advanced stages. Studies have pointed out that investigations into the molecular mechanisms underlying HCC, including mitochondrial dysfunction and
Scenario Analysis for Supply Chain Management of Milled Grain Products in South Africa: A System Dynamics Approach
This study aimed to identify the interactions between the sub-systems of the supply chain system of milled grain products, in South Africa, namely: (1) farming (agricultural); (2) transport (transportation); (3) manufacturing (milling); and (4) trade (retail). Furthermore, this paper investigated how these sub-systems are affected by economic and natural external factors namely: (1) the exchange
Natural products and long noncoding RNA signatures in gallbladder cancer: a review focuses on pathogenesis, diagnosis, and drug resistance
Gallbladder cancer (GBC) is an aggressive and lethal malignancy with a poor prognosis. Long noncoding RNAs (lncRNAs) and natural products have emerged as key orchestrators of cancer pathogenesis through widespread dysregulation across GBC transcriptomes. Functional studies have revealed that lncRNAs interact with oncoproteins and tumor suppressors to control proliferation, invasion, metastasis
Measuring the efficiency of banks using high-performance ensemble technique
The importance of technology and managerial risk management in banks has increased due to the financial crisis. Banks are the most affected since there are so many of them with poor financial standing. Due to this problem, an unstable and inefficient financial system causes economic stagnation in both the banking sector and overall economy. Data envelopment analysis (DEA) has been used to examine
Experimental and numerical investigation of preloaded recycled concrete beams strengthened with CFRP
Purpose: The use of recycled coarse aggregate in concrete structures promotes environmental sustainability; however, performance of these structures might be negatively impacted when it is used as a replacement to traditional aggregate. This paper aims to simulate recycled concrete beams strengthened with carbon fiber-reinforced polymer (CFRP), to advance the modeling and use of recycled concrete