Pharmacotherapy of PD and related movements disorders and their limitations

A wide range of neurodegenerative illnesses, including Parkinson's disease (PD) and related movement disorders, greatly impair the quality of life for those who are afflicted. This chapter provides a comprehensive overview of Parkinson's disease (PD), covering everything from the disease's basic definitions, epidemiology, and pathophysiology to the complex issues involved in treating its symptoms with medication and other approaches. It emphasizes the significance of adjunct therapies and a multidisciplinary approach in comprehensive care, as well as the crucial role that personalized medicine plays in adjusting treatments to meet the needs of each patient. The book also explores cutting edge future paths including gene and stem cell therapies and the revolutionary possibilities of technology in treatment planning. This chapter, which is intended for researchers and healthcare professionals, summarizes recent findings and developing patterns to highlight how treatment is still evolving. © 2025 Elsevier Inc. All rights reserved.