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Microbial acetylcholinesterase inhibitors for Alzheimer’s therapy: recent trends on extraction, detection, irradiation-assisted production improvement and nano-structured drug delivery

Abstract: Neurodegenerative disorders especially Alzheimer’s disease (AD) are significantly threatening the public health. Acetylcholinesterase (AChE) inhibitors are compounds of great interest which can be used as effective agents for the symptomatic treatment of AD. Although plants are considered the largest source for these types of inhibitors, the microbial production of AChE inhibitors represents an efficient, easily manipulated, eco-friendly, cost-effective, and alternative approach. This review highlights the recent advances on the microbial production of AChE inhibitors and summarizes

Energy and Water

Fabrication, Characterization and Optical Investigation of Semi-organic Nonlinear Alanine Hippurate Single Crystals

In the present work, a single crystal of alanine and hippuric acid was prepared through the slow growth dynamics of sample evaporation. The crystallinity, structure, and cell parameters of the produced single crystals were determined by X-ray diffraction (XRD) analysis. While, frequency shifting and the various functional groups of alanine with hippuric acid were investigated by FTIR and FT-Raman studies. In addition, grain size and the morphological shape of alanine hippurate (AH) single crystals were examined by FE-SEM analysis. Transmission of light through the grown material was defined by

Energy and Water

Engineered Nanomaterials as Potential Candidates for HIV Treatment: Between Opportunities and Challenges

Nanomaterials have received considerable attention due to their unique properties; they have high surface area compared to volume ratio, giving them superior chemical, optical and thermal characteristics. Nanomaterials have also both diagnostic and therapeutic applications. In this mini review, we are highlighting valuable data about human immunodeficiency virus (HIV), its relationship with cancer and its potential treatment with some nanomaterials such as silver nanoparticles (Ag NPs). © 2019, Springer Science+Business Media, LLC, part of Springer Nature.

Energy and Water

Ab initio density functional theory investigation of the interaction between carbon nanotubes and water molecules during water desalination Process

Density functional theory calculations using B3LYP/3-21G level of theory have been implemented on 6 carbon nanotubes (CNTs) structures (3 zigzag and 3 armchair CNTs) to study the energetics of the reverse osmosis during water desalination process. Calculations of the band gap, interaction energy, highest occupied molecular orbital, lowest unoccupied molecular orbital, electronegativity, hardness, and pressure of the system are discussed. The calculations showed that the water molecule that exists inside the CNT is about 2-3 Å away from its wall. The calculations have proven that the zigzag

Energy and Water

Merits of photocatalytic and antimicrobial applications of gamma-irradiated Co: XNi1- xFe2O4/SiO2/TiO2; X = 0.9 nanocomposite for pyridine removal and pathogenic bacteria/fungi disinfection: Implication for wastewater treatment

In this paper, we report a layer-by-layer approach for the preparation of a concentric recyclable composite (CoxNi1-xFe2O4/SiO2/TiO2; x = 0.9) designed for wastewater treatment. The prepared composite was investigated by X-ray diffraction spectroscopy, high-resolution transmission electron microscopy and scanning electron microscopy (SEM) supported with energy dispersive X-ray (EDX) spectroscopy to analyze crystallinity, average particle size, morphology and elemental composition, respectively. The antimicrobial activities of the prepared composite have been investigated against multi-drug

Energy and Water

Modelling of Cu2ZnSnSe4-CdS-ZnO thin film solar cell

We present a device model for the Cu2ZnSnSe4-CdS-ZnO solar cell with a total area efficiency of 9.7% reported in 2013 (Brammertz et al 2013 Appl. Phys. Lett. 103 163904). The simulations were performed using SCAPS program. In the device model, we reproduce rigorously the full range of layers and device properties estimated experientially using various characterization techniques. We include in the device model barriers at the back contact and the absorber/buffer interfaces, the photo-doped CdS buffer layer and defect states at the CdS/ZnO interface. A perfect match with the electrical

Energy and Water

A study on the feasibility of producing polylactic acid from cotton and coffee waste in Egypt

The amount of solid waste is growing In Egypt. It is estimated to be 20 million tons annually according to the Ministry of environment forecasts. The typical competence of collection in urban areas signifies 40 – 80%, although the middling proficiency of assortment processes and transport in rustic areas signifies 40 % which is considered hazardous for communal health and environment deprived of handling solid waste in integrated framework for solid waste management system. The reprocessing and treatment procedures in Egypt represent about 9.5 % of the entire urban solid waste, which is

Energy and Water

Frequency survey simulation for developing novel radio frequency energy harvesting model

Renewable Energy sources are the center of attraction for research and development all over the world nowadays, the demand of a lasting cheap source of energy that is environmental friendly, is the main challenge recently. Energy Harvesting is a new technology that is going to make a revolution in the coming decade. Energy Harvesting is a technique to provide alternative sources of energy that are environmental friendly and low in cost. Radio Frequency Energy Harvesting is one of the methods to provide electrical energy from the ambient Radio Frequency waves that already exists in the

Energy and Water
Circuit Theory and Applications

Numerical simulation of Oldroyd-B fluid with application to hemodynamics

Oldroyd-B viscoelastic fluid is numerically simulated using the stabilized Galerkin least squares finite element method. The instabilities due to the connective nature of the Oldroyd-B model is treated using the discrete viscous elastic split stress method. The model is used to study the behavior of the flow of blood through an abdominal aortic segment. The results show that the viscoelastic nature of the blood should be considered specially at low shear rates. © The Author(s) 2019.

Energy and Water

Comparison and analysis of water main performance models

Evaluating the condition state of infrastructure assets is one of the most integral pieces of information to the asset manager. Water infrastructure poses specific challenges compared to sewer infrastructure where techniques like CCTV are now being consistently used to assess condition. The number of water main breaks is commonly used as a proxy for water main condition. Statistical water main performance models rely on using past breakage patterns and rates to predict future performance of the water main network. Performance models can be broadly classified into two groups. Rate-of-failure

Energy and Water