Dr. Mohamed El-Hadidi

Nile tilapia, Oreochromis niloticus, is the principal fish bred in Egypt. A pilot study was designed to analyze the bacterial composition of the Nile tilapia fish guts from two saltwater lakes in Northern Egypt. Fish samples were obtained from two Delta lakes: Manzala (ML) and Borollus (BL). DNA was extracted, and the bacterial communities in the stomach content were classified (down to the

The scientific literature is full of studies that provide evidence highlighting the role of microbiome in type 2 diabetes (T2D) development and progression, still, discrepancies are evident when studying the link between certain taxonomic groupings and T2D, thus, eliminating the discrepancy between such studies is crucial to build on a robust systematic approach to identify the possible linkage

Antimicrobial resistance (AMR) is one of the ten dangers threatening our world, according to the world health organization (WHO). Nowadays, there are plenty of electronic microbial genomics and metagenomics data records that represent host-associated microbiomes. These data introduce new insights and a comprehensive understanding of the current antibiotic resistance threats and the upcoming

The human β-coronavirus SARS-CoV-2 epidemic started in late December 2019 in Wuhan, China. It causes Covid-19 disease which has become pandemic. Each of the five-known human β-coronaviruses has four major structural proteins (E, M, N and S) and 16 non-structural proteins encoded by ORF1a and ORF1b together (ORF1ab) that are involved in virus pathogenicity and infectivity. Here, we performed

Advanced Persistent Threat (APT) is a stealthy computer network attack. Its threat lies in the fact that unauthorized access to a network is gained and the attackers, whether a person or a group may remain undetected for an extended period. APT group can spread and gain access to the most valuable assets in the targeted organization. Depending on the tools used by APT group it can be hard and

In the current SARS-CoV2 pandemic, identification and differentiation between SARS-COV2 strains are vital to attain efficient therapeutic targeting, drug discovery and vaccination. In this study, we investigate how the viral genetic code mutated locally and what variations is the Egyptian population most susceptible to in comparison with different strains isolated from Asia, Europe and other

Infection with multiple drug resistant (MDR) Escherichia coli poses a life threat to immunocompromised pediatric cancer patients. Our aim is to genotypically characterize the plasmids harbored in MDR E. coli isolates recovered from bacteremic patients of Children’s Cancer Hospital in Egypt 57357 (CCHE 57357). In this study, 21 carbapenem-resistant E. coli (CRE) isolates were selected that exhibit

Mammalian protein-coding sequence detection provides a wide range of applications in biodiversity research, evolutionary studies, and understanding of genomic features. Representation of genomic sequences in Chaos Game Representation (CGR) helps reveal hidden features in DNA sequences due to its ability to represent sequences in both numerical and graphical levels. Machine learning approaches can

In 2017, pneumonia was the primary diagnosis for 1.3 million visits to the Emergency Department (ED) in the United States. The mortality rate was estimated to be 5%-10% of hospitalized patients, whereas it rises to 30% for severe cases admitted to the Intensive Care Unit (ICU). Among all cases admitted to ED, 30% were misdiagnosed, and they did not suffer from pneumonia, which raises a flag for