Hypoxia is one of the main hallmarks of hepatocellular carcinoma (HCC) resulting from improper oxygenation and insufficient nourishment of the HCC microenvironment. The effect of hypoxia is mediated by hypoxia-inducible factor-1A (HIF-1A) via targeting various downstream pathways, including glycolysis, angiogenesis, and survival signaling. However, HCC cell lines in a 2-dimensional (2D) setting do

Plasmonic photovoltaics integrate nanoparticles into the active layer to enhance power absorption. However a gap exists between simulated and experimental IV characteristics. Fabrication studies have attributed the issues to fabrication resolution, and recombination with no detailed step-by-step characterization. To address this issue, the paper presents a comprehensive optical and electrical

This paper reviews amplifier-based oscillator topologies and introduces new ones while reporting all possible circuits that can be obtained from some of them using exhaustive searching. Second-order as well as third-order RC and RLC oscillators are reported and selected circuits are designed and experimentally verified. Incorporating non-ideal and nonlinear effects into the modeling of these

The global rise in Metabolic dysfunction-associated steatotic liver disease (MASLD)/Metabolic dysfunction-associated steatohepatitis (MASH) highlights the urgent necessity for noninvasive biomarkers to detect these conditions early. To address this, we endeavored to construct a diagnostic model for MASLD/MASH using a combination of bioinformatics, molecular/biochemical data, and machine learning

The increasing adoption of programming education necessitates efficient and accurate methods for evaluating students’ coding assignments. Traditional manual grading is time-consuming, often inconsistent, and prone to subjective biases. This paper explores the application of large language models (LLMs) for the automated evaluation of programming assignments. LLMs can use advanced natural language

This study investigates the structural evolution, mechanical properties and high-temperature performance of a novel low-density refractory high entropy intermetallic alloy (RHEIA); Al12Nb25.5Ta8.5Ti27.5Zr26.5. The alloy was prepared by vacuum arc melting, homogenized and subjected to various heat treatments at 600°C, 800°C and 1000°C. The resulting microstructure was revealed using scanning

Carbon dioxide emissions pose a global issue, with deforestation, forest loss from logging, fires, and construction highlighting the adverse effects of climate change. Urgent action is required to reduce carbon dioxide emissions and preserve forests. Egypt can contribute to reducing greenhouse gas emissions by effectively utilizing its waste resources, especially agricultural waste. The research

The just-in-time concept, mass customization, omnichannel distribution, and the rising global population have all fueled the logistics sector. Consequently, using automation inside the warehouses to make them more dynamic and sustainable for the future is one of the crucial components to adapt to this quick shift. Giants in the industry and technology are becoming more interested in the “smart

Screw connections within sheathed cold formed steel (CFS) shear walls experience in-plane shear that acts in a parallel direction to the sheathing's free edge. Yet, many investigations focused on connections where shear loads applied perpendicular to the sheathing's free edge. Although the modes of failure in perpendicular testing are comparable to those ones in CFS shear walls, the load

Burning agricultural waste is a common practice among farmers in many countries, leading to global warming and climate change. Upcycling abundant agricultural waste will prevent incineration-generated hazards and provide sustainable and eco-friendly wood. An alternative wood composite was prepared using Aspergillus niger mycelium and exopolysaccharides (EPS) as a green binder. Autoclaving and