On the 28th & 29th of October 2019, Nile University hosted IEEE conference # 48431 Novel Intelligent and Leading Emerging Sciences conference (NILES 2019) in Cairo, Egypt. The conference aimed at providing a platform for researchers, engineers, academics and industrial professionals to present their recent research work and to explore future trends in various areas of engineering and technology, in four tracks, with the list of technical areas in each track. NILES 2019 featured plenary keynote speeches by a group of distinguished professors worldwide, Prof. Mohamed-Slim Alouini, Prof. Ahmed S. Elwakil & Prof. Costas Psychalinos . 2 best paper winners & one best poster winner were from the presented papers & posters were featured & honored during the event. The accepted papers will be reviewed and some of them will be submitted for inclusion on the IEEE Xplore.